How are hsCRP and sleep related?

The relationship between hsCRP (high-sensitivity C-reactive protein) and sleep has been studied extensively. hsCRP is a well-established inflammatory marker linked to cardiovascular risk. Epidemiological evidence consistently shows that short sleep duration (<6 hours) and poor sleep quality are associated with elevated hsCRP levels. Sleep disorders such as insomnia and obstructive sleep apnea also correlate with higher hsCRP. The evidence comes mainly from cross-sectional and longitudinal studies; some experimental sleep deprivation studies show acute increases in inflammatory markers. However, effect sizes are moderate, and many confounders (obesity, stress, diet) exist. Causality is not fully established. MyBody-X offers hsCRP testing, but it is a screening tool, not a diagnostic. Elevated hsCRP should be evaluated by a physician. Improving sleep hygiene may help lower inflammation, but it does not replace medical care.