DNA tests for seniors (e.g., from MyBody-X) can identify genetic variants related to drug metabolism (CYP2C19, MTHFR) or nutrient processing. However, effect sizes are small and clinical relevance in older age is often unclear. Seniors frequently take multiple medications – pharmacogenetic information could theoretically help, but consumer tests typically cover only single SNPs and not full metabolizer status. Age-specific reference ranges are lacking. Results should never be used alone for treatment decisions, only with a doctor's guidance. Many provider claims are exaggerated; actual benefit for healthy seniors is limited. Evidence: practice-based, no strong studies for this age group.
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