Myths vs facts: Fertility Check | Fruchtbarkeits-Test and weight loss

Myths vs. Facts: Fertility Check and Weight Loss Myth: A direct-to-consumer DNA test (e.g., from MyBody-X) can tell you exactly which supplements to take to improve fertility and lose weight. Fact: The evidence for such combined claims is weak. While certain gene variants (e.g., FTO, MTHFR, FADS2) can influence metabolism or hormone regulation, effect sizes are small and the evidence is mostly observational. Clinically established fertility markers such as AMH, FSH, or estradiol are not replaced by DNA tests. The link between fertility and weight is multifactorial: excess weight can impair fertility via insulin resistance and inflammation, but a DNA test alone does not provide personalized diet or supplement recommendations. Most cited studies are not reproducible or come from small cohorts. Moreover, pediatric validation is lacking (cf. context on children's DNA tests). Conclusion: Use DNA results as a hypothesis, not a prescription. Check blood levels before supplementing and consult a doctor or endocrinologist. A fertility check should include clinical parameters, not just genetics.