Magnesium plays a key role in skin health through its involvement in cell proliferation, DNA repair, and inflammation regulation. It acts as a cofactor for over 300 enzymes, including those essential for collagen synthesis and skin barrier function. Magnesium deficiency has been linked to increased skin sensitivity, dryness, acne, and impaired wound healing. However, most evidence comes from in vitro and observational studies; randomized controlled trials on magnesium supplementation for specific skin conditions are limited and inconsistent. The evidence for a direct therapeutic effect in conditions like eczema or psoriasis is therefore moderate to mechanistic. A blood test (serum or whole blood) can detect deficiency, but interpretation for skin health is not straightforward. If deficiency or skin issues are suspected, medical consultation is recommended before supplementation.
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