What to watch with Leaky Gut Test and menopause?

The term 'leaky gut' (increased intestinal permeability) is popular in functional medicine but is not a recognized medical diagnosis. Tests claiming to measure leaky gut (e.g., lactulose-mannitol test, zonulin levels) lack standardization and strong evidence. During menopause, declining estrogen levels can alter the gut microbiome and potentially affect gut barrier function. However, no specific test reliably diagnoses 'leaky gut in menopause.' Genetic tests offered by MyBody-X (e.g., LCT/MCM6 for lactose intolerance) or microbiome analyses may provide clues about digestive issues but cannot confirm leaky gut. Be cautious of marketing that overstates these tests. For persistent symptoms like bloating, fatigue, or joint pain, consult a doctor for proper evaluation. Overall, the evidence for leaky gut testing is mixed to weak.