What to watch with DNA Stoffwechseltest and fertility?

A DNA metabolism test typically analyzes genes like MTHFR, COMT, and CYP variants involved in processing nutrients and drugs. Regarding fertility, some evidence links MTHFR C677T to elevated homocysteine and recurrent pregnancy loss, but effect sizes are small and findings inconsistent. Other common metabolism genes (CYP1A2, CYP2C9) have no established direct role in fertility. Most associations come from GWAS or mechanistic studies, not clinical guidelines. Direct-to-consumer claims about 'fertility optimization' are often overstated. Lifestyle factors, hormonal balance, and medical evaluation are far more impactful. Do not make major dietary or supplement changes based solely on such DNA results without consulting a specialist.