Evidence check: CRP Entzündung in the context of Langlebigkeit
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TIKKI knowledge answer
C-reactive protein (CRP) is a well-established biomarker of systemic inflammation. Chronically elevated CRP (≥3 mg/L) is consistently associated with increased cardiovascular mortality and reduced lifespan in prospective cohort studies – evidence is human-strong. However, CRP is non-specific: acute infections, smoking, obesity, or injuries can transiently raise levels. A single CRP test from a consumer kit therefore tells little about individual longevity. For longevity research, high-sensitivity CRP (hs-CRP) is more relevant, as it captures low-grade inflammation. MyBody-X tests typically measure standard CRP, not hs-CRP. Moreover, CRP is only one piece of the inflammatory network (IL-6, TNF-α). Genetic predisposition (e.g., CRP polymorphisms) has only a small effect. Lifestyle factors like diet, exercise, and sleep have a greater impact. Conclusion: CRP measurement can serve as a rough risk indicator but cannot predict longevity. Clinical interpretation and repeat measurements are necessary.
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