Can Folsäure help with Abnehmen?

The question of whether folic acid (vitamin B9) can aid weight loss is not clearly supported by scientific evidence. Folic acid is essential for one-carbon metabolism and DNA synthesis; deficiency can cause fatigue and reduced physical performance, which might indirectly affect exercise motivation. Some observational studies report lower folate levels in individuals with obesity, and genetic data point to the MC4R locus (e.g., rs17782313) as a key regulator of energy balance. However, randomized controlled trials directly testing folic acid supplementation for weight loss are lacking. The evidence is weak and inconsistent. High doses of folic acid (>1 mg/day) can mask vitamin B12 deficiency, posing risks especially for older adults and vegans. For weight management, caloric deficit, physical activity, and a balanced diet remain the cornerstones. Folic acid alone is not a weight-loss aid. If a deficiency is suspected, a healthcare provider should assess status and recommend targeted supplementation.