Common mistakes around CRP (C-reactive protein) lab testing include: 1) Ignoring the reference range – a mildly elevated level (<10 mg/L) may indicate chronic inflammation (e.g., obesity, smoking) rather than acute infection. 2) Confusing standard CRP with high-sensitivity CRP (hs-CRP) – the latter is used for cardiovascular risk assessment. 3) Misinterpreting results during early infection – CRP rises 6–12 hours after onset; a normal value does not rule out early infection. 4) Failing to account for medications (statins, corticosteroids) or chronic conditions (rheumatoid arthritis, cancer). 5) Assuming a single value is sufficient – serial measurements are often needed. 6) Relying on home tests without clinical context – lab values alone are not diagnostic. Evidence is strong (clinical practice), but interpretation requires medical expertise.
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