Typical costs for a cortisol check vary widely depending on the test method and provider. Simple saliva tests measuring the diurnal cortisol rhythm (often 4–5 samples) range from $50 to $150 in the US, while more comprehensive panels including urine or hair cortisol can cost $200–$400 or more. Most of these tests are not covered by public health insurance unless medically indicated; they are often marketed as direct-to-consumer wellness tests. Private insurance may reimburse with a doctor's referral. Importantly, a single abnormal cortisol reading is not diagnostic for conditions like Cushing's or Addison's disease. The evidence for at-home cortisol testing is primarily based on practice and marketing rather than robust clinical validation. Caveat: results should always be interpreted by a physician, and follow-up lab testing (e.g., dexamethasone suppression test) is often needed. Without medical context, these tests can lead to unnecessary anxiety or false reassurance.
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