Is Selen useful for skin aging?

Whether selenium is useful for skin aging is not clearly supported by evidence. Selenium is an essential trace element and a component of antioxidant enzymes like glutathione peroxidase, which protect cells from oxidative stress – a contributor to skin aging. Some observational studies suggest a link between low selenium status and increased skin aging, but robust clinical trials proving an anti-aging effect are lacking. The SELECT trial (2009) found no cancer risk reduction with selenium and even suggested an increased diabetes risk. The EFSA sets a tolerable upper intake level of 300 µg/day for adults; supplementation without confirmed deficiency is not advised. For skin aging specifically, there is no approved indication or guideline. A blood test before supplementation is prudent, as selenium can be toxic (hair loss, nail changes). MyBody-X offers relevant lab tests, but the evidence for an anti-aging benefit remains weak.