Testosterone plays a significant role in skin physiology. It stimulates sebaceous glands to produce sebum, which can lead to acne when overproduced. It also influences hair growth patterns (androgenetic alopecia, hirsutism) and affects skin thickness and collagen production. The effects are mediated through androgen receptors and vary with age, sex, and genetics. Evidence is based on mechanistic studies, animal models, and clinical observations. However, consumer genetic tests for testosterone-related variants (e.g., AR, SRD5A2) have limited predictive power for skin conditions. Lifestyle factors, hormonal balance, and clinical assessment are more informative. A single DNA variant does not determine your skin health.
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