What role does Östradiol play in Schlaf?

Estradiol, the primary form of estrogen, plays a key role in sleep regulation. It modulates body temperature (promoting sleep onset by lowering core temperature) and influences neurotransmitters like serotonin and GABA that govern sleep-wake cycles. During the menstrual cycle, estradiol drops in the late luteal phase and during menopause, often leading to insomnia, night awakenings, and reduced sleep efficiency. Research shows that hormone replacement therapy can improve sleep quality in postmenopausal women. However, effects are individual and depend on age, cycle phase, and genetic variants (e.g., in ESR1). The evidence is human-strong, but not all sleep issues are hormonal – stress, lifestyle, and medical conditions must be considered. Caveat: MyBody-X tests are not diagnostic; consult a doctor for persistent sleep problems.