What role does ACTN3 play in skin aging?

The provided context does not include information on ACTN3 and skin aging. ACTN3 encodes α-actinin-3, a protein primarily expressed in fast-twitch muscle fibers and linked to sprint/power performance. Some exploratory studies have suggested possible associations with skin elasticity or collagen metabolism, but the evidence is weak and insufficient for clinical guidance. Most findings are mechanistic or associative, not from robust human trials. A direct role in skin aging is not established. Consumer DNA tests claiming such links are speculative. Without strong evidence, no specific supplements or dietary changes can be recommended. Sun protection, a balanced diet, and adequate hydration remain the cornerstones of skin health.