Is HLA-DQ2 useful for Wechseljahre?

HLA-DQ2 is a genetic marker for celiac disease, not for menopause. There is no scientific evidence that HLA-DQ2 is directly useful for menopause timing or symptoms. While untreated celiac disease can indirectly affect hormonal health via autoimmunity and malabsorption, this does not make HLA-DQ2 a menopause-relevant test. Direct-to-consumer tests should clearly state this limitation. For menopause, hormone panels (FSH, estradiol) or symptom tracking are more appropriate. The evidence level is 'unclear' because no direct studies link HLA-DQ2 to menopause.