What to watch with Leaky Gut Test and blood sugar?

Combining a leaky gut test with blood sugar measurements is not yet well-supported by evidence. Leaky gut tests (e.g., stool zonulin or lactulose/mannitol urine test) may indicate increased intestinal permeability, but methods are not standardized and individual interpretability is limited. Blood sugar markers (fasting glucose, HbA1c, continuous glucose monitoring) are well-validated for glucose metabolism. There is a mechanistic rationale: impaired gut barrier may promote inflammation and worsen insulin resistance. However, robust human studies showing clinical benefit from combined testing for diet or supplement choices are lacking. Caution: No consumer test replaces medical diagnosis. If blood sugar is elevated, consult a physician. The evidence for this combination is currently 'unclear' or 'mechanistic'.