Women’s Wellness Check | Frauen-Gesundheits-Test: which blood markers matter?

A standard Women’s Wellness Check should include the following blood markers based on current guidelines and common practice: **Complete Blood Count (CBC)** with hemoglobin, hematocrit, and red cell indices to detect anemia; **Iron status** (ferritin, transferrin, possibly soluble transferrin receptor) – especially relevant for women with heavy menstrual cycles or fatigue; **Vitamin D** (25-hydroxyvitamin D) – deficiency is widespread and linked to bone health, immune function, and mood (evidence: human-moderate). **Thyroid function** (TSH, optionally fT3/fT4) is critical because thyroid disorders are more common in women. **Fasting glucose** and **HbA1c** for diabetes screening; **Lipid panel** (total cholesterol, LDL, HDL, triglycerides) for cardiovascular risk assessment. **High-sensitivity CRP** as an inflammatory marker. For specific symptoms, **sex hormones** (estradiol, progesterone, testosterone, SHBG) may be considered, but routine screening is not recommended. **Note:** Evidence for most of these markers is solid, but a wellness check without symptoms should not be overinterpreted. Genetic tests (e.g., MTHFR) lack sufficient evidence for routine use. The window period for STI tests (see context) is not relevant for blood markers. Always follow up abnormal results with a physician.