What should I know about jojo effekt?

The yo-yo effect refers to the cycle of losing weight during a diet and then regaining it – often more than before. It is driven by metabolic adaptations (e.g., reduced resting energy expenditure) and behavioral factors like unsustainable eating patterns. DNA tests that claim to predict your risk for the yo-yo effect have very limited predictive power. Single SNPs explain <1% of weight variation, and polygenic scores are not validated for individual diet plans. Most weight loss success depends on adherence, not genetics. To avoid the yo-yo effect, focus on gradual, sustainable lifestyle changes rather than restrictive diets.