What to watch with HLA-DQ2 and sleep?

The provided context does not contain specific data on HLA-DQ2 and sleep. HLA-DQ2 is a genetic marker strongly associated with celiac disease. Sleep disturbances can occur in untreated celiac disease or non-celiac gluten sensitivity – possibly due to inflammatory processes or nutrient deficiencies (e.g., iron, vitamin D). However, a direct sleep-specific effect of HLA-DQ2 alone is not well established. Evidence is based on mechanistic reasoning and observational studies, not randomized controlled trials. If you are HLA-DQ2 positive and experience sleep issues, medical evaluation for celiac disease may be warranted. Watch for accompanying symptoms like fatigue, bloating, or diarrhea. Do not start a gluten-free diet without a confirmed diagnosis. The practical value of genetic tests is limited – they provide hints, not diagnoses.