Insulin and fertility are closely linked, primarily through Polycystic Ovary Syndrome (PCOS). Insulin resistance leads to compensatory hyperinsulinemia, which stimulates ovarian androgen production and disrupts ovulation. Even in non-PCOS women, impaired insulin sensitivity can affect menstrual regularity and conception. Lifestyle interventions that improve insulin sensitivity (e.g., diet, exercise) are associated with better fertility outcomes. However, the relationship is multifactorial and cannot be captured by a single test. Measuring fasting insulin or glucose may provide clues but is not a substitute for comprehensive fertility evaluation. The evidence is based on clinical practice and observational studies, not on the provided context. Caution: single biomarker results can be misleading without clinical correlation.
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