A general blood check-up should be tailored to age, risk factors, and symptoms. Core parameters include: complete blood count, kidney function (creatinine, urea), liver enzymes (ALT, AST, GGT), fasting glucose, lipid panel (cholesterol, triglycerides), electrolytes (sodium, potassium), and inflammatory markers like CRP (C-reactive protein). For specific symptoms or risks (e.g., family history of cardiovascular disease, diabetes, thyroid issues), extended tests such as HbA1c, TSH, vitamin D, or iron status may be useful. You should see a doctor if you receive abnormal results, experience unexplained symptoms (fatigue, weight changes, pain), or want preventive screening. Important: direct-to-consumer DNA tests (e.g., for CRP variants) provide only genetic predisposition hints, not diagnoses. They cannot replace clinical evaluation. Always have concerning results interpreted by a physician in the proper clinical context. Evidence supports regular check-ups for certain age groups (e.g., from age 35 in Germany), but frequency should be individualized.
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