Evidence check: Testosteron in the context of Haut
T
TIKKI knowledge answer
Testosterone affects the skin in several ways: it stimulates sebum production, promotes hair growth (e.g., beard), and can trigger acne in predisposed individuals. In the skin, testosterone is converted to dihydrotestosterone (DHT), which plays a key role in androgenetic alopecia (pattern hair loss). The evidence for these links is human-strong – supported by clinical studies and basic endocrinology. However, direct-to-consumer DNA tests for 'skin and testosterone' are generally not informative: variants in genes like AR (androgen receptor) or SRD5A2 (5α-reductase) are rarely included, and even when they are, the effect size is small and confounded by many factors. Effects on wound healing or collagen metabolism are mechanistically plausible but not well-established. For specific skin issues (acne, hair loss), consult a dermatologist or endocrinologist – a genetic test cannot replace hormone measurement. Bottom line: testosterone does impact skin, but consumer DNA tests offer little actionable guidance here.
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