Is HLA-DQ2 useful for longevity?

HLA-DQ2 is a genotype strongly associated with celiac disease. There is no direct evidence linking it to longevity. Undiagnosed celiac disease can impair health through chronic inflammation and nutrient malabsorption, potentially affecting lifespan, but most HLA-DQ2 carriers never develop celiac disease. Without clinical symptoms or positive antibodies, the test's utility for longevity is unclear. Evidence is mixed: strong for celiac risk, weak for longevity. Be cautious of overblown claims from direct-to-consumer tests.