How are FADS1 and Langlebigkeit related?

FADS1 (fatty acid desaturase 1) is a key enzyme in the conversion of omega-3 and omega-6 fatty acids. Genetic variants in FADS1 influence blood levels of long-chain polyunsaturated fatty acids, which are linked to inflammation and cardiovascular health. Some studies suggest a connection to longevity, as a favorable fatty acid profile may reduce age-related disease risk. However, the effect size of individual SNPs is modest, and the evidence is primarily from GWAS and observational studies. Causal evidence from intervention trials is lacking. Therefore, attributing longevity directly to a single gene is speculative. MyBody-X tests can detect these variants, but interpretation should consider overall lifestyle and other genetic factors.