Magnesium is frequently marketed as an anti-aging mineral, but the evidence for a direct effect on skin aging is limited. In vitro studies indicate that magnesium plays a role in DNA repair and collagen synthesis—processes that decline with age. Deficiency may increase inflammation and oxidative stress, potentially accelerating skin aging. However, large human trials demonstrating a clear anti-aging benefit from magnesium supplementation are lacking. Most data come from cell or animal models. Bioavailability varies: magnesium chloride and citrate are better absorbed than oxide. High doses can cause diarrhea, nausea, and in people with kidney impairment, dangerous electrolyte imbalances. A blood test (serum or whole blood) can identify deficiency before supplementing. Topical magnesium (e.g., magnesium oil) is sometimes used for skin, but its anti-wrinkle efficacy is not well-supported. In summary, magnesium is essential for skin health, but its role as a standalone anti-aging intervention is overhyped. A balanced diet rich in magnesium (nuts, whole grains, leafy greens) is more advisable than high-dose supplements.
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