Evidence check: CRP Entzündung in the context of longevity
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TIKKI knowledge answer
C-reactive protein (CRP) is a well-established biomarker of systemic inflammation. Chronically mildly elevated CRP levels (0.3–1.0 mg/L) are associated in large cohort studies with accelerated aging, cardiovascular disease, and increased all-cause mortality – making CRP relevant in the longevity context. However, the evidence is largely associative: CRP itself likely does not directly cause aging but reflects inflammatory processes driven by lifestyle (diet, exercise, sleep, stress). Genetic studies (GWAS) show that CRP variants explain only a small fraction of the variance. A single CRP measurement does not predict individual lifespan. MyBody-X measures CRP in blood, but the result should be interpreted as an indicator of inflammatory status, not a longevity diagnosis. For meaningful assessment, repeated measurements and additional markers (e.g., IL-6, TNF-α, albumin) are recommended. Safety note: Markedly elevated CRP (>10 mg/L) suggests acute infection or tissue damage – medical evaluation is required. Conclusion: CRP is a useful but non-specific longevity marker; evidence is human-strong for association but mechanistically incomplete.
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