MyBody-X angle on FTO Labor

The FTO gene locus is the most robustly associated genetic marker for obesity from GWAS. However, individual SNP effect sizes (e.g., rs9939609) are small, explaining only ~0.3% of BMI variance. MyBody-X may include this SNP, but clinical utility for personal diet planning is limited. Evidence is from population-wide association studies, not RCTs proving that dietary changes based on FTO improve outcomes. The provided context lacks specific FTO information, so a conservative stance is warranted: the test can indicate a statistical risk, but lifestyle factors dominate. No single-gene diet recommendation is evidence-based.