Evidence check: FUT2 in the context of menopause

FUT2 encodes a fucosyltransferase that determines secretor status and influences vitamin B12 absorption. During menopause, B12 levels often decline, and FUT2 variants could theoretically exacerbate this. However, no direct studies link FUT2 to menopausal symptoms or hormonal changes. The evidence is mechanistic and indirect. A DNA test may indicate a predisposition for lower B12, but it cannot replace blood testing. For menopause-related concerns, medical evaluation is essential. Consumer DNA tests have limited utility here.