IgE (immunoglobulin E) is primarily involved in allergic reactions and defense against parasites. There is no robust evidence supporting its use as a biomarker for longevity. Chronically elevated IgE may indicate an allergic diathesis or parasitic infection, but a direct link to aging processes or lifespan is not established. Longevity research focuses more on inflammatory markers like CRP, IL-6, or cellular aging markers such as telomere length. An IgE test alone is therefore not informative for longevity assessment. The evidence level is 'mechanistic' or 'unclear', as studies are mostly associative and lack causal proof. Consumers should not interpret IgE tests as 'longevity tests' but rather in the context of allergies or immune status.
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