Myths vs facts: Longevity DNA Test and Müdigkeit

Myths vs. facts: Longevity DNA test and fatigue. Such a test cannot directly diagnose or explain fatigue. Fatigue is multifactorial (sleep, stress, nutrition, exercise, medical conditions). The genes tested (e.g., PPARA, FTO, HTR2A) have only small effects on energy metabolism or stress response. Evidence is from GWAS, not clinical trials. A result may serve as a conversation starter but should not replace medical evaluation. For persistent fatigue, always rule out organic causes (thyroid, iron deficiency, sleep apnea).