Myths vs facts: IgE and Allergie

IgE antibodies are central to allergic reactions, but an elevated IgE level alone does not prove an allergy. Many people have high IgE without symptoms, and allergies can exist with normal IgE (non-IgE-mediated). Blood tests for specific IgE provide clues, but false positives are common – clinical confirmation by a specialist is essential. Genetic tests for allergy risk rely on small-effect SNPs and are not diagnostic. Under German law (GenDG), such tests require physician involvement. Evidence for IgE testing in practice is moderate, but interpretation requires expertise. Marketing often promises simple answers, yet reality is complex: IgE levels vary with age, environment, and infections. A negative test does not rule out allergy; a positive test does not confirm it. Fact: IgE is a tool, not a verdict.