What to watch with Magnesium and gut health?

Magnesium and gut health are connected, but the evidence is mostly mechanistic. Magnesium can influence gut motility (e.g., in constipation) and acts as a cofactor for many enzymes. Some studies suggest a role in microbiome regulation, but large clinical RCTs are lacking. At high doses (e.g., magnesium citrate), it can have a laxative effect – a known mechanism, but not proof of general gut health. Caution in kidney disease: magnesium can accumulate. A blood test for magnesium status is advisable before supplementation. MyBody-X tests do not provide direct guidance on magnesium; interpretation remains individual. Overall: magnesium is relevant, but not a magic bullet for the gut.