Myths vs facts: Vitamin D 25-OH and Abnehmen

Myth: Vitamin D directly causes weight loss. Fact: Low 25-OH vitamin D levels are common in obesity, but causality is unclear. Vitamin D is stored in adipose tissue, so higher body fat can lower circulating levels – this is likely a consequence rather than a cause. Randomized controlled trials show little to no effect of vitamin D supplementation on weight loss in individuals without deficiency. Correcting a deficiency is important for overall health, but expecting weight loss from supraphysiological doses is not supported. Genetic variants like VDR BsmI (rs1544410) have only a small effect; dosing should be based on measured 25-OH levels, not genotype alone. Evidence: human-moderate. Caveat: marketing often overstates; weight loss depends primarily on calorie balance and physical activity.