was kostet ein gentest beim mensch — which blood markers matter?

The cost of a human genetic test varies widely depending on scope and provider. Direct-to-consumer tests like 23andMe or MyBody-X typically cost €100–300, but they analyze mostly single SNPs with small effect sizes. Clinical whole-genome or exome sequencing ranges from €500–2000 and is covered by insurance only for medical indications. Regarding blood markers that matter for aging, cellular senescence markers such as p16INK4a, p21CIP1, inflammatory SASP factors (IL‑6, IL‑8), and matrix metalloproteinases (MMP‑1, MMP‑3, MMP‑9) have been associated with age-related decline. These markers increase with age but are not specific to senescence – they are confounded by inflammation, medications, and menstrual cycle. Currently, no standardized clinical test exists for biological age; measurements remain research-grade and are not validated for individual diagnosis. A pure DNA test cannot measure biological age or telomere length. Evidence for lifespan extension from SNP-based recommendations is lacking – no randomized controlled trials prove efficacy. Consumers should maintain realistic expectations: genetic tests offer clues, not proven anti-aging prescriptions.