Risks and limits of Gluten Basis

The question about risks and limits of gluten testing (e.g., DNA-based) is valid. The provided contexts do not directly address gluten, so the answer relies on general evidence. DNA tests for gluten sensitivity or celiac (e.g., HLA-DQ2/DQ8) can indicate genetic predispositions, but effect sizes are small and most associations come from population-level GWAS. A positive test does not guarantee clinically relevant gluten intolerance. Risks: unnecessary gluten-free diets may cause nutrient deficiencies (fiber, B vitamins), social restrictions, and higher costs. Limits: lack of pediatric validation, no predictive power for non-celiac gluten sensitivity, and evidence is mostly mechanistic or marketing-driven. Always consult a doctor before starting a gluten-free diet and consider antibody testing. Evidence is rated 'unclear' due to absence of specific sources.