What role does Progesteron play in Darmgesundheit?

Progesterone, a female sex hormone, influences gut health through several mechanisms. It slows gastrointestinal motility, which can lead to constipation, especially during pregnancy or the luteal phase. It also modulates the intestinal barrier and has anti-inflammatory effects via progesterone receptors in the gut. Some studies suggest interactions with the gut microbiome, but human evidence is moderate and often based on observational studies or animal models. MyBody-X or similar tests measure progesterone in blood or saliva, but interpretation for gut health is not standardized. Single measurements reveal little about complex hormonal regulation. High progesterone levels (e.g., in pregnancy) may affect gut permeability, but clinical relevance remains unclear. There are no established recommendations for progesterone supplementation to improve gut health. If hormonal imbalances with gut symptoms are suspected, a doctor should be consulted. The evidence is rated as human-moderate because human studies exist but lack large randomized controlled trials.