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What effect does manganese deficiency and Mn₂O₃ nanoparticle supplementation have on bone remodeling in rats?

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What effect does manganese deficiency and Mn₂O₃ nanoparticle supplementation have on bone remodeling in rats?

The study reported that both dietary manganese deficiency and supplementation with Mn₂O₃ nanoparticles disrupted normal bone remodeling and prevented proper maturation of the mineral matrix in rats.

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