What to watch with hsCRP and skin aging?

HsCRP (high-sensitivity C-reactive protein) is a general marker of systemic inflammation. Chronically elevated levels may contribute to skin aging by promoting collagen breakdown and oxidative stress, but hsCRP is not skin-specific. Evidence linking hsCRP directly to skin aging is mostly mechanistic and observational, not from large human trials. Consumer hsCRP tests can indicate inflammation, but results vary and should be confirmed by a doctor. Lifestyle factors (sun protection, diet, smoking, sleep) have a stronger impact on skin aging than hsCRP alone. No clinical guidelines recommend hsCRP-based skincare. Use hsCRP as a general health clue, not a skin aging predictor.