MEDI CHECK Speicheltest: which blood markers matter?

The MEDI CHECK saliva test is a DNA test that analyzes genetic variants – it does not directly measure blood markers. The question 'which blood markers matter' is therefore ambiguous: a saliva test provides genotypes, not current blood concentrations. However, to interpret the genetic results meaningfully, complementary blood markers can be useful. These include homocysteine (methylation, B-vitamin status), a lipid panel (total, LDL, HDL cholesterol, triglycerides), hs-CRP (systemic inflammation), vitamin D, and the omega-3 index. These markers are supported by moderate to strong evidence. Importantly, many commercial tests, especially IgG food panels, are not recommended by major allergy societies (AAAAI, EAACI) because they lack clinical validity for diagnosing food intolerances or allergies. The MEDI CHECK itself is a DNA test; blood markers should be measured separately under medical supervision. The evidence for individual genetic variants (e.g., SOD2 rs4880) is often mechanistic and insufficient for clinical decisions. Bottom line: Focus on established blood markers and consult a physician rather than relying on unvalidated test kits.