What role does Zöliakie Test play in Allergie?

A celiac test (e.g., tTG-IgA antibodies or HLA genetic markers) is designed to diagnose celiac disease, an autoimmune enteropathy triggered by gluten. It is not an allergy test. Allergies are IgE-mediated immediate reactions (e.g., wheat allergy), whereas celiac disease involves a delayed T‑cell-mediated response. In practice, a celiac test may be used in the workup of food intolerances to differentiate celiac disease from wheat allergy or non-celiac gluten sensitivity. However, the evidence for using celiac markers to diagnose allergies is weak – the underlying mechanisms are distinct. Direct-to-consumer tests that market celiac genes or antibodies as an 'allergy check' are misleading. Proper diagnosis requires clinical evaluation, possibly duodenal biopsy, and allergy tests (skin prick test, specific IgE). Without clinical context, a positive celiac test can be falsely interpreted as an allergy. In summary, the celiac test plays only an indirect, differential-diagnostic role in allergology and should not be mistaken for an allergy test.