Evidence check: Magnesium in the context of longevity

Magnesium is frequently linked to longevity due to its role in over 300 enzymatic reactions, including DNA repair, inflammation control, and mitochondrial function. Observational studies associate low magnesium levels with increased mortality and age-related diseases such as cardiovascular issues and type 2 diabetes. However, robust randomized controlled trials demonstrating that magnesium supplementation directly extends lifespan are lacking. The evidence is primarily mechanistic and observational. Avoiding deficiency is prudent, but excessive intake can be harmful (kidney issues, diarrhea). MyBody-X tests can measure blood magnesium, but a single value does not reflect total body stores. Longevity effects are individual and depend on diet, genetics, and lifestyle. Be cautious of exaggerated marketing claims.