What role does Zöliakie Test play in Fruchtbarkeit?

Celiac disease testing (e.g., tTG-IgA, EMA, duodenal biopsy) plays a significant role in unexplained infertility. Untreated celiac disease can impair fertility through malabsorption of key nutrients (iron, folate, vitamin D), hormonal imbalances, and chronic inflammation. Studies indicate a higher prevalence of undiagnosed celiac disease among women with unexplained infertility. After diagnosis and initiation of a gluten-free diet, pregnancy rates improve substantially. The test is clinically validated and recommended by guidelines. Importantly, it is a diagnostic test for an autoimmune condition, not a general fertility test. IgG-based tests for gluten sensitivity lack evidence and may lead to unnecessary dietary restrictions. Celiac testing should be considered in cases of unexplained infertility, recurrent miscarriage, or menstrual irregularities.