What role does HLA-DQ2 play in Abnehmen?

HLA-DQ2 is a genetic marker strongly associated with celiac disease. In untreated celiac disease, weight loss can occur due to malabsorption. However, in healthy individuals without celiac, HLA-DQ2 plays no direct role in weight loss. The evidence is mechanistic: the link exists only through gluten intolerance. A DNA test for HLA-DQ2 is not a weight-loss tool; it is used for celiac risk assessment. Those aiming to lose weight should focus on caloric balance, exercise, and a balanced diet – not single gene variants. Caveat: Without a medical diagnosis, a gluten-free diet should not be adopted solely for weight loss.