What role does Folsäure play in skin aging?

Folic acid (vitamin B9) is crucial for DNA synthesis and repair, as well as cell division. In skin, it supports epidermal regeneration and protection against UV-induced DNA damage, a key driver of premature skin aging (photoaging). Some studies suggest adequate folate intake may strengthen the skin barrier and promote collagen production, potentially reducing wrinkle formation. However, the evidence is moderate: most data come from in vitro or animal studies, and human intervention trials are limited. Additionally, high doses of synthetic folic acid can be problematic for individuals with certain genetic variants (e.g., MTHFR). For skin health, a balanced diet rich in natural folate (leafy greens, legumes) is likely more beneficial than high-dose supplements. MyBody-X tests can analyze genetic predispositions in folate metabolism, but direct translation to skin aging remains speculative. Overall, folic acid plays a supportive but not primary role in anti-aging.