When combining MY FOODBOOK (a personalized nutrition plan based on DNA and biomarker analysis) with menopause (Wechseljahre), caution is warranted. Menopause involves hormonal shifts that affect metabolism, bone density, and cardiovascular risk. A foodbook based on genetic data may offer insights, but the evidence for direct, clinically meaningful effects is often weak. Focus on SNPs with stronger evidence, such as GCKR for triglycerides, but note that many lipid-related variants have small effect sizes. Lifestyle factors (exercise, sleep, stress) remain dominant. For supplements like vitamin D3/K2, which are often recommended during menopause, test your levels first to avoid toxicity. The evidence for personalized nutrition in menopause is mostly mechanistic or observational; large randomized trials are lacking. Use the foodbook as a guide, not a prescription, and discuss any changes with a healthcare professional. Be skeptical of marketing claims that overstate genetic influence.
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