What to watch with CYP1A2 and Sport?

The provided contexts contain no information about CYP1A2 and sport. Therefore, I must rely on general knowledge: CYP1A2 is the primary enzyme metabolizing caffeine. Genetic variants (e.g., rs762551) classify individuals as fast or slow metabolizers. For athletes, slow metabolizers face increased risk of cardiovascular side effects (elevated blood pressure, palpitations) with high caffeine intake before exercise. Fast metabolizers can safely use caffeine as an ergogenic aid. The evidence for this is human-moderate, but not supported by the given context. Without specific data from the provided sources, I recommend caution: a CYP1A2 DNA test can offer guidance, but should not be the sole basis for supplementation decisions. Consult a sports medicine professional.