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Evidence check: AMH in the context of fatigue

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Evidence check: AMH in the context of fatigue

The use of AMH (Anti-Müllerian Hormone) in the context of fatigue is not scientifically established. AMH is a validated marker of ovarian reserve used in fertility medicine. Some studies suggest a link between low AMH and perimenopausal symptoms including fatigue, but the evidence is weak and insufficient for clinical recommendation. Fatigue has many causes (e.g., sleep deprivation, stress, thyroid dysfunction, iron deficiency), and an AMH test alone cannot address these. The test is also highly age-dependent and subject to natural variation. Interpretation without gynecological context is misleading. MyBody-X does not offer an AMH test; the provided context contains no AMH information. Therefore, the evidence is rated as unclear. For persistent fatigue, a comprehensive medical evaluation is recommended, not an isolated hormone test.

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