Myths vs facts: FUT2 and Haut

Claims that FUT2 variants directly affect skin health are not supported by the provided evidence. FUT2 (fucosyltransferase 2) is best known as the 'secretor' gene: it determines whether fucosylated glycans are expressed in bodily fluids like saliva and gut secretions. These glycans influence gut microbiome composition and have been linked to vitamin B12 levels in GWAS (human-strong). A plausible indirect link to skin conditions via the microbiome or immune modulation exists, but no direct clinical studies in the provided context validate FUT2 as a skin gene. The gut-skin axis is an active research area, but specific associations with acne, eczema, or barrier function remain speculative. Direct-to-consumer tests marketing FUT2 as a 'skin gene' overstate the evidence. A blood B12 test and gut health assessment are more actionable than genetic interpretation. Safety note: For skin concerns, consult a dermatologist rather than relying solely on DNA results.