What to watch with Cortisol senken and longevity?

To lower cortisol and support longevity, focus on sleep hygiene, light exposure, and stress management. Chronic cortisol elevation from sleep deprivation or circadian disruption can accelerate aging. Genetic tests (e.g., for CLOCK variants) only indicate a slight tendency toward later sleep (10–25 min effect), not poor health per se. The real driver is sleep debt. In shift workers, low melatonin reflects circadian disruption, not aging; melatonin supplements (1–3 mg) help only with proper light hygiene. Gut microbiome tests claiming 'imbalance' often lack clinical validation – a balanced diet and regular exercise are more reliable. Longevity is polygenic and lifestyle-driven; single variants like SIRT1 have negligible predictive power. Bottom line: invest in evidence-based habits, not unvalidated tests.