Cortisol tests for women, such as home saliva or blood spot kits, have significant limitations. Cortisol levels follow a circadian rhythm and are influenced by stress, sleep, diet, and menstrual cycle phase. A single measurement cannot reliably diagnose conditions like Cushing's syndrome or adrenal insufficiency. The concept of 'adrenal fatigue' is not supported by evidence. Consumer cortisol tests lack clinical validation and often use non-standardized reference ranges. They are marketed as wellness tools but should not replace medical evaluation. Risks include false reassurance or unnecessary worry. For persistent symptoms like fatigue, weight changes, or mood issues, consult a doctor for proper testing (e.g., serum cortisol, ACTH stimulation test). Evidence: marketing/unclear.
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